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T Petteri Piepponen Selected Research

Multiple Endocrine Neoplasia Type 2b (MEN 3)

1/2018Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine.
8/2011Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals.
6/2008Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine.
5/2007Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra.

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T Petteri Piepponen Research Topics

Disease

7Parkinson Disease (Parkinson's Disease)
06/2020 - 02/2009
4Multiple Endocrine Neoplasia Type 2b (MEN 3)
01/2018 - 05/2007
2Neoplasms (Cancer)
06/2020 - 05/2007
2Neurodegenerative Diseases (Neurodegenerative Disease)
08/2018 - 01/2017
1Schizophrenia (Dementia Praecox)
08/2022
1Psychotic Disorders (Schizoaffective Disorder)
08/2022
1Brain Diseases (Brain Disorder)
08/2018
1Mental Disorders (Mental Disorder)
01/2017
1Prostatic Neoplasms (Prostate Cancer)
01/2014
1Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis)
05/2007

Drug/Important Bio-Agent (IBA)

8Dopamine (Intropin)FDA LinkGeneric
08/2022 - 05/2007
6Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
08/2022 - 12/2015
4Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
01/2019 - 05/2007
2Nerve Growth Factors (Neurotrophins)IBA
08/2018 - 01/2018
2Amphetamine (Amfetamine)FDA LinkGeneric
01/2018 - 08/2011
2Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
01/2017 - 06/2008
2Proteins (Proteins, Gene)FDA Link
02/2009 - 05/2007
1Biological ProductsIBA
08/2018
16-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
01/2018
1alpha-SynucleinIBA
01/2018
1lactacystinIBA
12/2015
1Proteasome InhibitorsIBA
12/2015
1prostatic acid phosphataseIBA
01/2014
1NeurotoxinsIBA
08/2011
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
08/2011
1Oxidopamine (6 Hydroxydopamine)IBA
08/2011
1alpha-Methyltyrosine (Metirosine)FDA Link
06/2008
1Tetrabenazine (Nitoman)FDA Link
06/2008
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
05/2007
1Cocaine (Cocaine HCl)IBA
05/2007
1Messenger RNA (mRNA)IBA
05/2007

Therapy/Procedure

1Therapeutics
08/2018
1Deep Brain Stimulation
01/2018